Allergic pancytopenia to trimethoprim-sulphamethoxazole for Pneumocystis carinii pneumonia following methotrexate treatment for rheumatoid arthritis.
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چکیده
منابع مشابه
Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for rheumatoid arthritis.
Low dose methotrexate has been used effectively for various rheumatic and non-rheumatic diseases. Three cases of Pneumocystis carinii pneumonia occurring during treatment of rheumatoid arthritis with low dose methotrexate are presented. Several mechanisms might contribute to impaired immunity and the rare development of opportunist lung infection with methotrexate. A high degree of suspicion ma...
متن کاملPoor rectal absorption of trimethoprim/sulphamethoxazole in treating Pneumocystis carinii pneumonia.
A 24-year-old female with Hodgkin's disease and Pneumocystis carinii pneumonia was tested with trimethoprim/sulphamethoxazole (TMP/SMX) tablets. Because treatment failure was feared owing to chronic emesis potentially resulting in incomplete drug absorption, the same TMP/SMX dose was administered by rectal suppositories after the 5th day of oral dosing. The relative fractions (rectal/oral) or t...
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A case of Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriasis and psoriatic arthropathy is described. This potentially fatal event was probably precipitated by an interaction between methotrexate and concurrent non-steroidal anti-inflammatory drugs, resulting in serious potentiation of the effects of methotrexate.
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nuclei of the brainstem. In this theory, she attributes to the dorsal noradrenergic (locus coeruleus) system a role in processing exteroceptive cues; that is, enabling the animal to respond to significant environmental information. Alternatively, in this theory, the ventral system (non-locus coeruleus), which provides significant noradrenergic input to the hypothalamus, plays an interoceptive r...
متن کاملTreatment and prophylaxis of Pneumocystis carinii pneumonia.
Trimethoprim-sulfamethoxazole and parenteral pentamidine isethionate are effective in 60 to 80 per cent of AIDS patients with pneumocystis pneumonia. Adverse reactions are frequent with both agents, but because the adverse reactions are less severe with trimethoprim-sulfamethoxazole, this agent is the drug of choice for patients who are not known to be intolerant of it. The recommended duration...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1999
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/38.5.475